SCOPe 2.06: Domain d3quda_: 3qud A:

Lineage for d3quda_ (3qud A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56130] (185 PDB entries)

8. Domain d3quda_: 3qud A: [215425]
   automated match to d4eh4a_
   complexed with bog, n3f

Details for d3quda_

PDB Entry: 3qud, 2 Å

PDB Description: human p38 map kinase in complex with 2-amino-phenylamino-benzophenone

PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d3quda_:

Sequence, based on SEQRES records:

>d3quda_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records):

>d3quda_ d.144.1.7 (A:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtdvatrwyr
apeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkk
issesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfa
qyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Timeline for d3quda_:

• d3quda_ first appeared in SCOPe 2.03
  
• d3quda_ appears in SCOPe 2.05
  
• d3quda_ appears in SCOPe 2.07
  
• d3quda_ appears in the current release, SCOPe 2.08