SCOPe 2.08: Domain d3qlha2: 3qlh A:430-554

Lineage for d3qlha2 (3qlh A:430-554)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.0: automated matches [191357] (1 protein)
   not a true family

6. Protein automated matches [190396] (40 species)
   not a true protein

7. Species Human immunodeficiency virus type 1 [TaxId:11678] [225971] (19 PDB entries)

8. Domain d3qlha2: 3qlh A:430-554 [215287]
   Other proteins in same PDB: d3qlha1, d3qlha3, d3qlhb_
   automated match to d1hqea1
   complexed with dms, edo, mn, mnk, t27

Details for d3qlha2

PDB Entry: 3qlh, 2.7 Å

PDB Description: hiv-1 reverse transcriptase in complex with manicol at the rnase h active site and tmc278 (rilpivirine) at the nnrti binding pocket

PDB Compounds: (A:) Reverse transcriptase/ribonuclease H

SCOPe Domain Sequences for d3qlha2:

Sequence; same for both SEQRES and ATOM records:

>d3qlha2 c.55.3.0 (A:430-554) automated matches {Human immunodeficiency virus type 1 [TaxId: 11678]}
ekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvd
klvsa

Timeline for d3qlha2:

• d3qlha2 first appeared in SCOPe 2.03
  
• d3qlha2 appears in SCOPe 2.07