SCOPe 2.01: Domain d1adqa2: 1adq A:342-443

Lineage for d1adqa2 (1adq A:342-443)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma [88589] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88590] (28 PDB entries)
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d1adqa2: 1adq A:342-443 [21519]
   Other proteins in same PDB: d1adqa1, d1adqh1, d1adqh2, d1adql1, d1adql2
   part of a Fc

Details for d1adqa2

PDB Entry: 1adq, 3.15 Å

PDB Description: crystal structure of a human igm rheumatoid factor fab in complex with its autoantigen igg fc

PDB Compounds: (A:) igg4 rea fc

SCOPe Domain Sequences for d1adqa2:

Sequence; same for both SEQRES and ATOM records:

>d1adqa2 b.1.1.2 (A:342-443) Immunoglobulin heavy chain gamma constant domain 3, CH3-gamma {Human (Homo sapiens) [TaxId: 9606]}
qprepqvytlppsqeemtknqvsltclvkgfypsdiavewesngqpennykttppvldsd
gsfflysrltvdksrwqegnvfscsvmhealhnhytqkslsl

Timeline for d1adqa2:

• d1adqa2 first appeared (with stable ids) in SCOP 1.55
  
• d1adqa2 appears in SCOP 1.75
  
• d1adqa2 appears in SCOPe 2.02
  
• d1adqa2 appears in the current release, SCOPe 2.08