SCOPe 2.08: Domain d3qcja_: 3qcj A:

Lineage for d3qcja_ (3qcj A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d3qcja_: 3qcj A: [215161]
   automated match to d1yfoa_
   complexed with nx4

Details for d3qcja_

PDB Entry: 3qcj, 2.26 Å

PDB Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2-yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid

PDB Compounds: (A:) Receptor-type tyrosine-protein phosphatase gamma

SCOPe Domain Sequences for d3qcja_:

Sequence, based on SEQRES records:

>d3qcja_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqnt
giivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntkvkkg
qkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagv
grtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Sequence, based on observed residues (ATOM records):

>d3qcja_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgi
ivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntkqnervv
iqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlq
qikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Timeline for d3qcja_:

• d3qcja_ first appeared in SCOPe 2.03
  
• d3qcja_ appears in SCOPe 2.07