Lineage for d1b2wl2 (1b2w L:108-214)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1755446Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1755447Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1758822Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1761687Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 1761688Species Human (Homo sapiens) [TaxId:9606] [88569] (144 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 1761869Domain d1b2wl2: 1b2w L:108-214 [21298]
    Other proteins in same PDB: d1b2wh1, d1b2wh2, d1b2wl1
    part of a humanized anti-gamma-interferon Fab

Details for d1b2wl2

PDB Entry: 1b2w (more details), 2.9 Å

PDB Description: comparison of the three-dimensional structures of a humanized and a chimeric fab of an anti-gamma-interferon antibody
PDB Compounds: (L:) protein (antibody (light chain))

SCOPe Domain Sequences for d1b2wl2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1b2wl2 b.1.1.2 (L:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOPe Domain Coordinates for d1b2wl2:

Click to download the PDB-style file with coordinates for d1b2wl2.
(The format of our PDB-style files is described here.)

Timeline for d1b2wl2:

View in 3D
Domains from same chain:
(mouse over for more information)
d1b2wl1