SCOP 1.73: Domain d1fnsl2: 1fns L:108-214

Lineage for d1fnsl2 (1fns L:108-214)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (311 PDB entries)

8. Domain d1fnsl2: 1fns L:108-214 [21280]
   Other proteins in same PDB: d1fnsa_, d1fnsh1, d1fnsh2, d1fnsl1
   part of Fab NMC-4 blocking the von willebrand factor (vwf) a1 domain function
   mutant

Details for d1fnsl2

PDB Entry: 1fns, 2 Å

PDB Description: crystal structure of the von willebrand factor (vwf) a1 domain i546v mutant in complex with the function blocking fab nmc4

PDB Compounds: (L:) immunoglobulin nmc-4 igg1

SCOP Domain Sequences for d1fnsl2:

Sequence; same for both SEQRES and ATOM records:

>d1fnsl2 b.1.1.2 (L:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d1fnsl2:

• d1fnsl2 first appeared (with stable ids) in SCOP 1.55
  
• d1fnsl2 appears in SCOP 1.71
  
• d1fnsl2 appears in SCOP 1.75
  
• d1fnsl2 appears in the current release, SCOPe 2.08