Lineage for d12e8m2 (12e8 M:108-214)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 218897Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 218898Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 220405Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)
  6. 220881Protein Immunoglobulin (constant domains of L and H chains) [48972] (185 species)
  7. 221258Species Fab 2E8 (mouse), kappa L chain [49066] (1 PDB entry)
    specific to the low density lipoprotein receptor binding region of apolipoprotein E
  8. 221261Domain d12e8m2: 12e8 M:108-214 [21270]
    Other proteins in same PDB: d12e8h1, d12e8l1, d12e8m1, d12e8p1

Details for d12e8m2

PDB Entry: 12e8 (more details), 1.9 Å

PDB Description: 2e8 fab fragment

SCOP Domain Sequences for d12e8m2:

Sequence; same for both SEQRES and ATOM records: (download)

>d12e8m2 b.1.1.2 (M:108-214) Immunoglobulin (constant domains of L and H chains) {Fab 2E8 (mouse), kappa L chain}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnsatdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

SCOP Domain Coordinates for d12e8m2:

Click to download the PDB-style file with coordinates for d12e8m2.
(The format of our PDB-style files is described here.)

Timeline for d12e8m2: