SCOPe 2.05: Domain d12e8l2: 12e8 L:108-214

Lineage for d12e8l2 (12e8 L:108-214)

Root: SCOPe 2.05
Class b: All beta proteins [48724] (176 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families)
Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

Species Mouse (Mus musculus) [TaxId:10090] [88567] (346 PDB entries)
Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

Domain d12e8l2: 12e8 L:108-214 [21268]
Other proteins in same PDB: d12e8h1, d12e8h2, d12e8l1, d12e8m1, d12e8p1, d12e8p2
part of Fab 2E8 specific to the low density lipoprotein receptor binding region of apolipoprotein E

Details for d12e8l2

PDB Entry: 12e8 (more details), 1.9 Å

PDB Description: 2e8 fab fragment

PDB Compounds: (L:) igg1-kappa 2e8 fab (light chain)

SCOPe Domain Sequences for d12e8l2:

Sequence; same for both SEQRES and ATOM records: (download)

>d12e8l2 b.1.1.2 (L:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnsatdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

SCOPe Domain Coordinates for d12e8l2:

Click to download the PDB-style file with coordinates for d12e8l2.
(The format of our PDB-style files is described here.)

Timeline for d12e8l2: