SCOP 1.73: Domain d1g9mh2: 1g9m H:130-229

Lineage for d1g9mh2 (1g9m H:130-229)

Root: SCOP 1.73
Class b: All beta proteins [48724] (165 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (4 families)
Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)
Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (5 species)
Species Human (Homo sapiens) [TaxId:9606] [88575] (150 PDB entries)
including humanized antibodies (chimeric proteins with human constant domains)

Domain d1g9mh2: 1g9m H:130-229 [21263]
Other proteins in same PDB: d1g9mc1, d1g9mc2, d1g9mg_, d1g9mh1, d1g9ml1, d1g9ml2
part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
complexed with fuc, ioh, nag; mutant

Details for d1g9mh2

PDB Entry: 1g9m (more details), 2.2 Å

PDB Description: hiv-1 hxbc2 gp120 envelope glycoprotein complexed with cd4 and induced neutralizing antibody 17b

PDB Compounds: (H:) antibody 17b, heavy chain

SCOP Domain Sequences for d1g9mh2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1g9mh2 b.1.1.2 (H:130-229) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
stkgpsvfplapsskstsggtaalgclvkdyfpqpvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

SCOP Domain Coordinates for d1g9mh2:

Click to download the PDB-style file with coordinates for d1g9mh2.
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Timeline for d1g9mh2: