SCOPe 2.03: Domain d3kjda1: 3kjd A:226-364

Lineage for d3kjda1 (3kjd A:226-364)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
   core: 4 helices: bundle; unusual topology

4. Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families)
   duplication: consists of 2 helix-loop-helix structural repeats
   automatically mapped to Pfam PF02877

5. Family a.41.1.0: automated matches [227223] (1 protein)
   not a true family

6. Protein automated matches [226964] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225405] (21 PDB entries)

8. Domain d3kjda1: 3kjd A:226-364 [212388]
   Other proteins in same PDB: d3kjda2, d3kjdb2
   automated match to d1gs0a1
   protein/DNA complex; complexed with 78p, gol

Details for d3kjda1

PDB Entry: 3kjd, 1.95 Å

PDB Description: Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888

PDB Compounds: (A:) Poly [ADP-ribose] polymerase 2

SCOPe Domain Sequences for d3kjda1:

Sequence, based on SEQRES records:

>d3kjda1 a.41.1.0 (A:226-364) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyqslkki
edciragqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdieiaik
lvktelqspehpldqhyrn

Sequence, based on observed residues (ATOM records):

>d3kjda1 a.41.1.0 (A:226-364) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tenlyfqsmdlrvqeliklicnvqameemmmemkyntkkaplgkltvaqikagyqslkki
edciragqhgralmeacnefytriphdfglrtpplirtqkelsekiqllealgdieiaik
lvkspehpldqhyrn

Timeline for d3kjda1:

• d3kjda1 is new in SCOPe 2.03-stable
  
• d3kjda1 appears in SCOPe 2.04
  
• d3kjda1 appears in the current release, SCOPe 2.08