Lineage for d3kc3i_ (3kc3 I:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673283Protein MAP kinase activated protein kinase 2, mapkap2 [82789] (1 species)
    CaMK group; MAPKAPK subfamily; serine/threonine kinase
  7. 1673284Species Human (Homo sapiens) [TaxId:9606] [82790] (14 PDB entries)
  8. 1673318Domain d3kc3i_: 3kc3 I: [212281]
    automated match to d1nxkc_
    complexed with mk2

Details for d3kc3i_

PDB Entry: 3kc3 (more details), 2.9 Å

PDB Description: MK2 complexed to inhibitor N4-(7-(benzofuran-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine
PDB Compounds: (I:) MAP kinase-activated protein kinase 2

SCOPe Domain Sequences for d3kc3i_:

Sequence, based on SEQRES records: (download)

>d3kc3i_ d.144.1.7 (I:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
qfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarre
velhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqaftereas
eimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettshnslttpc
ytpyyvapevlgpekydkscdmwslgvimyillcgyppfysnhglaispgmktrirmgqy
efpnpewsevseevkmlirnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlke
dkerwedvkeem

Sequence, based on observed residues (ATOM records): (download)

>d3kc3i_ d.144.1.7 (I:) MAP kinase activated protein kinase 2, mapkap2 {Human (Homo sapiens) [TaxId: 9606]}
qfhvksglqikknaiiddykvtsqvlglgingkvlqifnkrtqekfalkmlqdcpkarre
velhwrasqcphivrivdvyenlyagrkcllivmecldggelfsriqdrgdqaftereas
eimksigeaiqylhsiniahrdvkpenllytskrpnailkltdfgfakettyvapevlgp
ekydkscdmwslgvimyillcgyppfysnispgmktrirmgqyefpnpewsevseevkml
irnllkteptqrmtitefmnhpwimqstkvpqtplhtsrvlkedkerwedvkeem

SCOPe Domain Coordinates for d3kc3i_:

Click to download the PDB-style file with coordinates for d3kc3i_.
(The format of our PDB-style files is described here.)

Timeline for d3kc3i_: