SCOP 1.63: Domain d1hyxh2: 1hyx H:114-215

Lineage for d1hyxh2 (1hyx H:114-215)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)

6. Protein Immunoglobulin (constant domains of L and H chains) [48972] (185 species)

7. Species Fab 6D9 (mouse), kappa L chain [49048] (2 PDB entries)
   hydrolytic antibody

8. Domain d1hyxh2: 1hyx H:114-215 [21191]
   Other proteins in same PDB: d1hyxh1, d1hyxl1
   complexed with cpd

Details for d1hyxh2

PDB Entry: 1hyx, 1.8 Å

PDB Description: high resolution crystal structure of the complex of the hydrolytic antibody fab 6d9 and a transition-state analog

SCOP Domain Sequences for d1hyxh2:

Sequence; same for both SEQRES and ATOM records:

>d1hyxh2 b.1.1.2 (H:114-215) Immunoglobulin (constant domains of L and H chains) {Fab 6D9 (mouse), kappa L chain}
akttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsd
lytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

Timeline for d1hyxh2:

• d1hyxh2 first appeared (with stable ids) in SCOP 1.55
  
• d1hyxh2 appears in SCOP 1.61
  
• d1hyxh2 appears in SCOP 1.65
  
• d1hyxh2 last appears in SCOP 1.73