Lineage for d3is4a1 (3is4 A:1-87,A:187-357)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) (S)
  5. Family c.1.12.1: Pyruvate kinase [51622] (1 protein)
  6. Protein Pyruvate kinase, N-terminal domain [51623] (6 species)
    this domain is interrupted by an all-beta domain
    C-terminal domain is alpha/beta
  7. Species Trypanosome (Leishmania mexicana) [TaxId:5665] [51626] (11 PDB entries)
  8. Domain d3is4a1: 3is4 A:1-87,A:187-357 [211863]
    Other proteins in same PDB: d3is4a2, d3is4a3, d3is4b2, d3is4b3
    automated match to d1pkla2
    complexed with gol, ptk

Details for d3is4a1

PDB Entry: 3is4 (more details), 2.1 Å

PDB Description: crystal structure of leishmania mexicana pyruvate kinase (lmpyk)in complex with 1,3,6,8-pyrenetetrasulfonic acid
PDB Compounds: (A:) pyruvate kinase

SCOPe Domain Sequences for d3is4a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d3is4a1 c.1.12.1 (A:1-87,A:187-357) Pyruvate kinase, N-terminal domain {Trypanosome (Leishmania mexicana) [TaxId: 5665]}

SCOPe Domain Coordinates for d3is4a1 are not available.

Timeline for d3is4a1:

Domains from same chain:
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d3is4a2, d3is4a3
Domains from other chains:
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d3is4b1, d3is4b2, d3is4b3