Lineage for d1aj7l2 (1aj7 L:110-214)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1290587Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1293251Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)
  7. 1293252Species Human (Homo sapiens) [TaxId:9606] [88569] (147 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody
  8. 1293299Domain d1aj7l2: 1aj7 L:110-214 [21116]
    Other proteins in same PDB: d1aj7h1, d1aj7h2, d1aj7l1
    part of humanized Fab 48G7
    complexed with npe

Details for d1aj7l2

PDB Entry: 1aj7 (more details), 2.1 Å

PDB Description: immunoglobulin 48g7 germline fab antibody complexed with hapten 5-(para-nitrophenyl phosphonate)-pentanoic acid. affinity maturation of an esterolytic antibody
PDB Compounds: (L:) immunoglobulin 48g7 fab (light chain)

SCOPe Domain Sequences for d1aj7l2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1aj7l2 b.1.1.2 (L:110-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
vaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdsk
dstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOPe Domain Coordinates for d1aj7l2:

Click to download the PDB-style file with coordinates for d1aj7l2.
(The format of our PDB-style files is described here.)

Timeline for d1aj7l2:

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Domains from same chain:
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d1aj7l1