SCOP 1.69: Domain d1aj7l2: 1aj7 L:110-214

Lineage for d1aj7l2 (1aj7 L:110-214)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (78 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)

8. Domain d1aj7l2: 1aj7 L:110-214 [21116]
   Other proteins in same PDB: d1aj7h1, d1aj7h2, d1aj7l1
   part of humanized Fab 48G7

Details for d1aj7l2

PDB Entry: 1aj7, 2.1 Å

PDB Description: immunoglobulin 48g7 germline fab antibody complexed with hapten 5-(para-nitrophenyl phosphonate)-pentanoic acid. affinity maturation of an esterolytic antibody

SCOP Domain Sequences for d1aj7l2:

Sequence; same for both SEQRES and ATOM records:

>d1aj7l2 b.1.1.2 (L:110-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens)}
vaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdsk
dstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d1aj7l2:

• d1aj7l2 first appeared (with stable ids) in SCOP 1.55
  
• d1aj7l2 appears in SCOP 1.67
  
• d1aj7l2 appears in SCOP 1.71
  
• d1aj7l2 appears in the current release, SCOPe 2.08