SCOPe 2.03: Domain d3hmia_: 3hmi A:

Lineage for d3hmia_ (3hmi A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d3hmia_: 3hmi A: [211129]
   automated match to d1m52b_
   complexed with dki

Details for d3hmia_

PDB Entry: 3hmi, 1.65 Å

PDB Description: the crystal structure of human abl2 in complex with 5-amino-3-{[4- (aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4- triazole-1-carbothioamide

PDB Compounds: (A:) Tyrosine-protein kinase ABL2

SCOPe Domain Sequences for d3hmia_:

Sequence; same for both SEQRES and ATOM records:

>d3hmia_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dkwemertditmkhklgggqygevyvgvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctleppfyivteympygnlldylrecnreevtavvllymatqissame
ylekknfihrdlaarnclvgenhvvkvadfglsrlmtgdtytahagakfpikwtapesla
yntfsiksdvwafgvllweiatygmspypgidlsqvydllekgyrmeqpegcppkvyelm
racwkwspadrpsfaethqafetmfhds

Timeline for d3hmia_:

• d3hmia_ is new in SCOPe 2.03-stable
  
• d3hmia_ appears in SCOPe 2.04
  
• d3hmia_ appears in the current release, SCOPe 2.08