SCOPe 2.03: Domain d3ha7a_: 3ha7 A:

Lineage for d3ha7a_ (3ha7 A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.18: Mycolic acid cyclopropane synthase [69560] (7 proteins)

6. Protein Methoxy mycolic acid synthase 4, Mma4 [142591] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [142592] (5 PDB entries)
   Uniprot Q79FX8 22-301

8. Domain d3ha7a_: 3ha7 A: [210948]
   automated match to d2fk7a1
   complexed with b32

Details for d3ha7a_

PDB Entry: 3ha7, 2.35 Å

PDB Description: Crystal structure of HMA (MMAA4) from mycobacterium tuberculosis complexed with S-adenosyl-N-decyl-aminoethyl (SADAE)

PDB Compounds: (A:) methoxy mycolic acid synthase 4

SCOPe Domain Sequences for d3ha7a_:

Sequence, based on SEQRES records:

>d3ha7a_ c.66.1.18 (A:) Methoxy mycolic acid synthase 4, Mma4 {Mycobacterium tuberculosis [TaxId: 1773]}
vsddffalfqdptrtyscayfeppeltleeaqyakvdlnldkldlkpgmtlldigcgwgt
tmrraverfdvnvigltlsknqharceqvlasidtnrsrqvllqgwedfaepvdrivsie
afehfghenyddffkrcfnimpadgrmtvqssvsyhpyemaargkklsfetarfikfivt
eifpggrlpstemmvehgekagftvpeplslrphyiktlriwgdtlqsnkdkaievtsee
vynrymkylrgcehyftdemldcslvtylkpgaa

Sequence, based on observed residues (ATOM records):

>d3ha7a_ c.66.1.18 (A:) Methoxy mycolic acid synthase 4, Mma4 {Mycobacterium tuberculosis [TaxId: 1773]}
vsddffalfqdptrtyscayfeppeltleeaqyakvdlnldkldlkpgmtlldigcgwgt
tmrraverfdvnvigltlsknqharceqvlasidtnrsrqvllqgwedfaepvdrivsie
afehfghenyddffkrcfnimpadgrmtvqssvsyhpyeargkklsfetarfikfivtei
fpggrlpstemmvehgekagftvpeplslrphyiktlriwgdtlqsnkdkaieveevynr
ymkylrgcehyftdemldcslvtylkpgaa

Timeline for d3ha7a_:

• d3ha7a_ is new in SCOPe 2.03-stable
  
• d3ha7a_ appears in SCOPe 2.04
  
• d3ha7a_ appears in the current release, SCOPe 2.08