SCOPe 2.08: Domain d3geqa1: 3geq A:251-533

Lineage for d3geqa1 (3geq A:251-533)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (3 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (56 PDB entries)

8. Domain d3geqa1: 3geq A:251-533 [210515]
   Other proteins in same PDB: d3geqa2, d3geqb2
   automated match to d2z8ca1
   complexed with pp2

Details for d3geqa1

PDB Entry: 3geq, 2.2 Å

PDB Description: structural basis for the chemical rescue of src kinase activity

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d3geqa1:

Sequence, based on SEQRES records:

>d3geqa1 d.144.1.7 (A:251-533) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
qtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqe
aqvmkklrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqi
asgmayvermnyvhrdlaaanilvgenlvckvadfglarliedneytarqgakfpikwta
peaalygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpes
lhdlmcqcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d3geqa1 d.144.1.7 (A:251-533) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
qtqglakdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqe
aqvmkklrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqi
asgmayvermnyvhrdlaaanilvgenlvckvadfglarlpikwtapeaalygrftiksd
vwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpe
erptfeylqafledyftstepqyqpgenl

Timeline for d3geqa1:

• d3geqa1 first appeared in SCOPe 2.03, called d3geqa_
  
• d3geqa1 appears in SCOPe 2.07