Lineage for d1fvea2 (1fve A:109-214)

  1. Root: SCOP 1.59
  2. 101936Class b: All beta proteins [48724] (110 folds)
  3. 101937Fold b.1: Immunoglobulin-like beta-sandwich [48725] (15 superfamilies)
  4. 101938Superfamily b.1.1: Immunoglobulin [48726] (6 families) (S)
  5. 103279Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)
  6. 103650Protein Immunoglobulin (constant domains of L and H chains) [48972] (169 species)
  7. 104007Species Fab 4D5 (synthetic, humanised version), kappa L chain [48992] (2 PDB entries)
  8. 104012Domain d1fvea2: 1fve A:109-214 [20966]
    Other proteins in same PDB: d1fvea1, d1fveb1, d1fvec1, d1fved1

Details for d1fvea2

PDB Entry: 1fve (more details), 2.7 Å

PDB Description: x-ray structures of the antigen-binding domains from three variants of humanized anti-p185-her2 antibody 4d5 and comparison with molecular modeling

SCOP Domain Sequences for d1fvea2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1fvea2 b.1.1.2 (A:109-214) Immunoglobulin (constant domains of L and H chains) {Fab 4D5 (synthetic, humanised version), kappa L chain}
tvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqds
kdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

SCOP Domain Coordinates for d1fvea2:

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Timeline for d1fvea2: