SCOPe 2.08: Domain d3etdd2: 3etd D:209-501

Lineage for d3etdd2 (3etd D:209-501)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (12 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein automated matches [227005] (6 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [225674] (6 PDB entries)

8. Domain d3etdd2: 3etd D:209-501 [209646]
   Other proteins in same PDB: d3etda1, d3etdb1, d3etdc1, d3etdd1, d3etde1, d3etdf1
   automated match to d1nr7a1
   complexed with b1t, glu, gtp, ndp

Details for d3etdd2

PDB Entry: 3etd, 2.5 Å

PDB Description: structure of glutamate dehydrogenase complexed with bithionol

PDB Compounds: (D:) GLUD1 protein

SCOPe Domain Sequences for d3etdd2:

Sequence; same for both SEQRES and ATOM records:

>d3etdd2 c.2.1.7 (D:209-501) automated matches {Cow (Bos taurus) [TaxId: 9913]}
hgrisatgrgvfhgienfineasymsilgmtpgfgdktfavqgfgnvglhsmrylhrfga
kcvavgesdgsiwnpdgidpkeledfklqhgtilgfpkakiyegsilevdcdilipaase
kqltksnaprvkakiiaegangpttpeadkiflernimvipdlylnaggvtvsyfewlkn
lnhvsygrltfkyerdsnyhllmsvqeslerkfgkhggtipivptaefqdrisgasekdi
vhsglaytmersarqimrtamkynlgldlrtaayvnaiekvfrvyneagvtft

Timeline for d3etdd2:

• d3etdd2 first appeared in SCOPe 2.03
  
• d3etdd2 appears in SCOPe 2.07