Lineage for d2fgwh2 (2fgw H:125-228)

  1. Root: SCOP 1.63
  2. 218896Class b: All beta proteins [48724] (119 folds)
  3. 218897Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 218898Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 220405Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)
  6. 220881Protein Immunoglobulin (constant domains of L and H chains) [48972] (185 species)
  7. 221528Species Fab H52 (synthetic, humanised version), kappa L chain [48990] (1 PDB entry)
  8. 221529Domain d2fgwh2: 2fgw H:125-228 [20957]
    Other proteins in same PDB: d2fgwh1, d2fgwl1

Details for d2fgwh2

PDB Entry: 2fgw (more details), 3 Å

PDB Description: x-ray structures of fragments from binding and nonbinding versions of a humanized anti-cd18 antibody: structural indications of the key role of vh residues 59 to 65

SCOP Domain Sequences for d2fgwh2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fgwh2 b.1.1.2 (H:125-228) Immunoglobulin (constant domains of L and H chains) {Fab H52 (synthetic, humanised version), kappa L chain}
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscd

SCOP Domain Coordinates for d2fgwh2:

Click to download the PDB-style file with coordinates for d2fgwh2.
(The format of our PDB-style files is described here.)

Timeline for d2fgwh2:

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Domains from same chain:
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d2fgwh1