SCOPe 2.02: Domain d1fail2: 1fai L:109-214

Lineage for d1fail2 (1fai L:109-214)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (317 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d1fail2: 1fai L:109-214 [20948]
   Other proteins in same PDB: d1faih1, d1faih2, d1fail1
   part of Fab R19.9

Details for d1fail2

PDB Entry: 1fai, 2.7 Å

PDB Description: three-dimensional structure of two crystal forms of fab r19.9, from a monoclonal anti-arsonate antibody

PDB Compounds: (L:) igg2b-kappa r19.9 fab (light chain)

SCOPe Domain Sequences for d1fail2:

Sequence; same for both SEQRES and ATOM records:

>d1fail2 b.1.1.2 (L:109-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqds
kdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d1fail2:

• d1fail2 first appeared (with stable ids) in SCOP 1.55
  
• d1fail2 appears in SCOPe 2.01
  
• d1fail2 appears in SCOPe 2.03
  
• d1fail2 appears in the current release, SCOPe 2.08