SCOPe 2.07: Domain d3d6tb_: 3d6t B:

Lineage for d3d6tb_ (3d6t B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.0: automated matches [191323] (1 protein)
   not a true family

6. Protein automated matches [190123] (156 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186862] (202 PDB entries)

8. Domain d3d6tb_: 3d6t B: [209033]
   automated match to d3bc1e_
   complexed with gdp, mg

Details for d3d6tb_

PDB Entry: 3d6t, 2.43 Å

PDB Description: structure of the roc domain from the parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric gtpase

PDB Compounds: (B:) Leucine-rich repeat serine/threonine-protein kinase 2

SCOPe Domain Sequences for d3d6tb_:

Sequence, based on SEQRES records:

>d3d6tb_ c.37.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mklmivgntgsgkttllqqlmktkksdlgmqsatvgidvkdwpiqirdkrkrdlvlnvwd
fagreefysthphfmtqralylavydlskgqaevdamkpwlfnikarassspvilvgthl
dvsdekqrkacmskitkellnkrgfpairdyhfvnateesdalaklrktii

Sequence, based on observed residues (ATOM records):

>d3d6tb_ c.37.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mklmivgntgsgkttllqlmgidvkdwplvlvwdfagreefysthphfmtqralylavyd
lskgqaevdamkpwlfnikarassspvilvgthldvsdkillgfpairdyhfvnateesl
rktii

Timeline for d3d6tb_:

• d3d6tb_ first appeared in SCOPe 2.03
  
• d3d6tb_ appears in SCOPe 2.06
  
• d3d6tb_ appears in the current release, SCOPe 2.08, called d3d6tb1