Lineage for d1bbjh2 (1bbj H:116-212)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1510240Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1510241Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1513476Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1515183Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (6 species)
  7. 1515187Species Human (Homo sapiens) [TaxId:9606] [88575] (179 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 1515438Domain d1bbjh2: 1bbj H:116-212 [20895]
    Other proteins in same PDB: d1bbja1, d1bbja2, d1bbjb1, d1bbjh1, d1bbjl1, d1bbjl2
    part of humanized Fab B72.3

Details for d1bbjh2

PDB Entry: 1bbj (more details), 3.1 Å

PDB Description: crystal structure of a chimeric fab' fragment of an antibody binding tumour cells
PDB Compounds: (H:) igg4-kappa b72.3 fab (heavy chain)

SCOPe Domain Sequences for d1bbjh2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1bbjh2 b.1.1.2 (H:116-212) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1bbjh2:

Click to download the PDB-style file with coordinates for d1bbjh2.
(The format of our PDB-style files is described here.)

Timeline for d1bbjh2: