SCOPe 2.07: Domain d3bpca2: 3bpc A:108-213

Lineage for d3bpca2 (3bpc A:108-213)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (368 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d3bpca2: 3bpc A:108-213 [208687]
   Other proteins in same PDB: d3bpca1, d3bpcb1, d3bpcb2
   automated match to d3t65a2
   complexed with kda, kdb, mg, zn

Details for d3bpca2

PDB Entry: 3bpc, 1.85 Å

PDB Description: co-crystal structure of s25-2 fab in complex with 5-deoxy-4-epi-2,3- dehydro kdo (4.8) kdo

PDB Compounds: (A:) Fab, antibody fragment (IgG1k), light chain

SCOPe Domain Sequences for d3bpca2:

Sequence, based on SEQRES records:

>d3bpca2 b.1.1.2 (A:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqds
kdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Sequence, based on observed residues (ATOM records):

>d3bpca2 b.1.1.2 (A:108-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgsegvlnswtdqdskds
tysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d3bpca2:

• d3bpca2 first appeared in SCOPe 2.03
  
• d3bpca2 appears in SCOPe 2.06
  
• d3bpca2 appears in the current release, SCOPe 2.08