SCOPe 2.01: Domain d1hsae_: 1hsa E:

Lineage for d1hsae_ (1hsa E:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (5 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (328 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d1hsae_: 1hsa E: [20735]
   Other proteins in same PDB: d1hsaa1, d1hsaa2, d1hsad1, d1hsad2

Details for d1hsae_

PDB Entry: 1hsa, 2.1 Å

PDB Description: the three-dimensional structure of hla-b27 at 2.1 angstroms resolution suggests a general mechanism for tight peptide binding to mhc

PDB Compounds: (E:) beta 2-microglobulin

SCOPe Domain Sequences for d1hsae_:

Sequence; same for both SEQRES and ATOM records:

>d1hsae_ b.1.1.2 (E:) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d1hsae_:

• d1hsae_ first appeared (with stable ids) in SCOP 1.55, called d1hsae1
  
• d1hsae_ appears in SCOP 1.75
  
• d1hsae_ appears in SCOPe 2.02
  
• d1hsae_ appears in the current release, SCOPe 2.08