SCOP 1.63: Domain d1qr1b_: 1qr1 B:

Lineage for d1qr1b_ (1qr1 B:)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (9 proteins)

6. Protein Class I MHC, beta2-microglobulin and alpha-3 domain [48945] (20 species)

7. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [48948] (29 PDB entries)

8. Domain d1qr1b_: 1qr1 B: [20713]
   Other proteins in same PDB: d1qr1a2, d1qr1d2

Details for d1qr1b_

PDB Entry: 1qr1, 2.4 Å

PDB Description: poor binding of a her-2/neu epitope (gp2) to hla-a2.1 is due to a lack of interactions in the center of the peptide

SCOP Domain Sequences for d1qr1b_:

Sequence; same for both SEQRES and ATOM records:

>d1qr1b_ b.1.1.2 (B:) Class I MHC, beta2-microglobulin and alpha-3 domain {Human (Homo sapiens), HLA-A2.1}
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d1qr1b_:

• d1qr1b_ first appeared (with stable ids) in SCOP 1.55, called d1qr1b1
  
• d1qr1b_ was called d1qr1b1 in SCOP 1.61
  
• d1qr1b_ appears in SCOP 1.65
  
• d1qr1b_ appears in the current release, SCOPe 2.08