SCOP 1.65: Domain d1breb_: 1bre B:

Lineage for d1breb_ (1bre B:)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogeneous CDRs are listed as engineered species

7. Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88520] (16 PDB entries)

8. Domain d1breb_: 1bre B: [20539]

Details for d1breb_

PDB Entry: 1bre, 2 Å

PDB Description: immunoglobulin light chain protein

SCOP Domain Sequences for d1breb_:

Sequence; same for both SEQRES and ATOM records:

>d1breb_ b.1.1.1 (B:) Immunoglobulin light chain kappa variable domain, VL-kappa {Human (Homo sapiens), cluster 1}
diqmtqspsslsasvgdrvtitcqasqdisdyliwyqqklgkapnlliydastletgvps
rfsgsgsgteytftisslqpediatyycqqyddlpytfgqgtkveik

Timeline for d1breb_:

• d1breb_ first appeared (with stable ids) in SCOP 1.55
  
• d1breb_ appears in SCOP 1.63
  
• d1breb_ appears in SCOP 1.67
  
• d1breb_ appears in the current release, SCOPe 2.08