SCOPe 2.03: Domain d2onia_: 2oni A:

Lineage for d2onia_ (2oni A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

5. Family d.148.1.0: automated matches [227207] (1 protein)
   not a true family

6. Protein automated matches [226939] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225255] (6 PDB entries)

8. Domain d2onia_: 2oni A: [205341]
   automated match to d1nd7a_
   complexed with na

Details for d2onia_

PDB Entry: 2oni, 2.2 Å

PDB Description: Catalytic Domain of the Human NEDD4-like E3 Ligase

PDB Compounds: (A:) E3 ubiquitin-protein ligase NEDD4-like protein

SCOPe Domain Sequences for d2onia_:

Sequence, based on SEQRES records:

>d2onia_ d.148.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lyfqgsrefkqkydyfrkklkkpadipnrfemklhrnnifeesyrrimsvkrpdvlkarl
wiefesekgldyggvarewffllskemfnpyyglfeysatdnytlqinpnsglcnedhls
yftfigrvaglavfhgklldgffirpfykmmlgkqitlndmesvdseyynslkwilendp
teldlmfcideenfgqtyqvdlkpngseimvtnenkreyidlviqwrfvnrvqkqmnafl
egftellpidlikifdenelellmcglgdvdvndwrqhsiykngycpnhpviqwfwkavl
lmdaekrirllqfvtgtsrvpmngfaelygsngpqlftieqwgspeklprahtcfnrldl
ppyetfedlrekllmave

Sequence, based on observed residues (ATOM records):

>d2onia_ d.148.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lyfqgsrefkqkydyfrkklkkpadipnrfemklhrnnifeesyrrimsvkrpdvlkarl
wiefeekgldyggvarewffllskemfnpyyglfeysatdnytlqinpnsglcnedhlsy
ftfigrvaglavfhgklldgffirpfykmmlgkqitlndmesvdseyynslkwilendpt
eldlmfcideenfgqtyqvdlkpngseimvtnenkreyidlviqwrfvnrvqkqmnafle
gftellpidlikifdenelellmcglgdvdvndwrqhsiykngycpnhpviqwfwkavll
mdaekrirllqfvtgtsrvpmngfaelygsngpqlftieqwgspeklprahtcfnrldlp
pyetfedlrekllmave

Timeline for d2onia_:

• d2onia_ is new in SCOPe 2.03-stable
  
• d2onia_ appears in SCOPe 2.04
  
• d2onia_ appears in the current release, SCOPe 2.08, called d2onia1