Lineage for d1ivlb_ (1ivl B:)

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1288590Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1288591Species Engineered (including hybrid species) [88533] (61 PDB entries)
    SQ NA # humanized antidoby; bactericidal Fab-h6831 ! SQ NA # Humanized antibody ! SQ NA # humanized antibody ! SQ NA # engineered antibody
  8. 1288610Domain d1ivlb_: 1ivl B: [20517]
    VL domain of synthetic antibody M29B; "reversed" dimerisation mode
    complexed with ipa

Details for d1ivlb_

PDB Entry: 1ivl (more details), 2.17 Å

PDB Description: the de novo design of an antibody combining site: crystallographic analysis of the vl domain confirms the structural model
PDB Compounds: (B:) igg-kappa m29b fv (light chain)

SCOPe Domain Sequences for d1ivlb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ivlb_ b.1.1.1 (B:) Immunoglobulin light chain kappa variable domain, VL-kappa {Engineered (including hybrid species)}

SCOPe Domain Coordinates for d1ivlb_:

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Timeline for d1ivlb_: