SCOPe 2.08: Domain d2iipa1: 2iip A:-8-260

Lineage for d2iipa1 (2iip A:-8-260)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.0: automated matches [191451] (1 protein)
   not a true family

6. Protein automated matches [190689] (87 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187871] (37 PDB entries)

8. Domain d2iipa1: 2iip A:-8-260 [204792]
   Other proteins in same PDB: d2iipa2, d2iipb2
   automated match to d2i62b_
   complexed with sah

Details for d2iipa1

PDB Entry: 2iip, 2.05 Å

PDB Description: human nicotinamide n-methyltransferase

PDB Compounds: (A:) Nicotinamide N-methyltransferase

SCOPe Domain Sequences for d2iipa1:

Sequence, based on SEQRES records:

>d2iipa1 c.66.1.0 (A:-8-260) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ssglvprgsmesgftskdtylshfnprdylekyykfgsrhsaesqilkhllknlfkifcl
dgvkgdllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvv
tyvcdlegnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacp
dlptycralrnlgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagyt
iewfevisqsysstmanneglfslvarkl

Sequence, based on observed residues (ATOM records):

>d2iipa1 c.66.1.0 (A:-8-260) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ssglvprgsmesgftskdtylshfnprdylekyyksaesqilkhllknlfkifcldgvkg
dllidigsgptiyqllsacesfkeivvtdysdqnlqelekwlkaapaafdwspvvtyvcd
legnrvkgpekeeklrqavkqvlkcdvtqsqplgavplppadcvlstlcldaacpdlpty
cralrnlgsllkpggflvimdalkssyymigeqkfsslplgreaveaavkeagytiewfe
visqsysstmanneglfslvarkl

Timeline for d2iipa1:

• d2iipa1 first appeared in SCOPe 2.03, called d2iipa_
  
• d2iipa1 appears in SCOPe 2.07