Lineage for d2ih1a1 (2ih1 A:1-118)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1510240Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1510241Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1510242Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1510447Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1510931Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (178 PDB entries)
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor
  8. 1511029Domain d2ih1a1: 2ih1 A:1-118 [204777]
    Other proteins in same PDB: d2ih1a2, d2ih1b1, d2ih1b2, d2ih1c_
    automated match to d1r3jb1
    complexed with 1em, k

Details for d2ih1a1

PDB Entry: 2ih1 (more details), 2.4 Å

PDB Description: ion selectivity in a semi-synthetic k+ channel locked in the conductive conformation
PDB Compounds: (A:) Fab heavy chain

SCOPe Domain Sequences for d2ih1a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ih1a1 b.1.1.1 (A:1-118) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qvqlqqpgaelvkpgasvklsckasgytftsdwihwvkqrpghglewigeiipsygrany
nekiqkkatltadkssstafmqlssltsedsavyycarergdgyfavwgagttvtvss

SCOPe Domain Coordinates for d2ih1a1:

Click to download the PDB-style file with coordinates for d2ih1a1.
(The format of our PDB-style files is described here.)

Timeline for d2ih1a1: