SCOP 1.71: Domain d1c5cl1: 1c5c L:1-107

Lineage for d1c5cl1 (1c5c L:1-107)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (170 PDB entries)

8. Domain d1c5cl1: 1c5c L:1-107 [20474]
   Other proteins in same PDB: d1c5ch1, d1c5ch2, d1c5cl2
   part of humanized catalytic Fab 21D8 with a decarboxylase activity
   complexed with gol, tk4

Details for d1c5cl1

PDB Entry: 1c5c, 1.61 Å

PDB Description: decarboxylase catalytic antibody 21d8-hapten complex

SCOP Domain Sequences for d1c5cl1:

Sequence; same for both SEQRES and ATOM records:

>d1c5cl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
eiqltqspsslsaslgervsltcrtsqeisgylswlqqkpdgtikrliydatkldsgapk
rfsgsrsgsdysltisslesedfadyyclqyasfprtfgggtkleik

Timeline for d1c5cl1:

• d1c5cl1 first appeared (with stable ids) in SCOP 1.55
  
• d1c5cl1 appears in SCOP 1.69
  
• d1c5cl1 appears in SCOP 1.73
  
• d1c5cl1 appears in the current release, SCOPe 2.08