SCOPe 2.08: Domain d2i3ua_: 2i3u A:

Lineage for d2i3ua_ (2i3u A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d2i3ua_: 2i3u A: [204697]
   automated match to d2h04a_

Details for d2i3ua_

PDB Entry: 2i3u, 1.85 Å

PDB Description: Structural studies of protein tyrosine phosphatase beta catalytic domain in complex with inhibitors

PDB Compounds: (A:) Receptor-type tyrosine-protein phosphatase beta

SCOPe Domain Sequences for d2i3ua_:

Sequence, based on SEQRES records:

>d2i3ua_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ktscpikinqfeghfmklqadsnyllskeyeelkdvgrnqscdiallpenrgknrynnil
pydatrvklsnvdddpcsdyinasyipgnnfrreyivtqgplpgtkddfwkmvweqnvhn
ivmvtqcvekgrvkcdhywpadqdslyygdlilqmlsesvlpewtirefkicgeeqldah
rlirhfhytvwpdhgvpettqsliqfvrtvrdyinrspgagptvvhcsagvgrtgtfial
drilqqldskdsvdiygavhdlrlhrvhmvqtecqyvylhqcvrdvlrarklr

Sequence, based on observed residues (ATOM records):

>d2i3ua_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ktscpikinqfeghfmklqadsnyllskeyeelkdvgrnqscdiallpenrgknrynnil
pydatrvklsnsdyinasyipgnnfrreyivtqgplpgtkddfwkmvweqnvhnivmvth
ywpadqdslyygdlilqmlsesvlpewtirefkicgeeqldahrlirhfhytvwpdhgvp
ettqsliqfvrtvrdyinrspgagptvvhcsagvgrtgtfialdrilqqldskdsvdiyg
avhdlrlhrvhmvqtecqyvylhqcvrdvlrarklr

Timeline for d2i3ua_:

• d2i3ua_ first appeared in SCOPe 2.03
  
• d2i3ua_ appears in SCOPe 2.07