Lineage for d2hz4c_ (2hz4 C:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1433649Protein Abelsone tyrosine kinase (abl) [56166] (2 species)
    PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase
  7. 1433650Species Human (Homo sapiens) [TaxId:9606] [226825] (5 PDB entries)
  8. 1433662Domain d2hz4c_: 2hz4 C: [204670]
    automated match to d2e2ba_
    complexed with 4st

Details for d2hz4c_

PDB Entry: 2hz4 (more details), 2.8 Å

PDB Description: abl kinase domain unligated and in complex with tetrahydrostaurosporine
PDB Compounds: (C:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2hz4c_:

Sequence, based on SEQRES records: (download)

>d2hz4c_ d.144.1.7 (C:) Abelsone tyrosine kinase (abl) {Human (Homo sapiens) [TaxId: 9606]}
kwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmkei
khpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissamey
lekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslay
nkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmr
acwqwnpsdrpsfaeihqafetmfqes

Sequence, based on observed residues (ATOM records): (download)

>d2hz4c_ d.144.1.7 (C:) Abelsone tyrosine kinase (abl) {Human (Homo sapiens) [TaxId: 9606]}
kwemertditmkhklgevyegvwkkytvavktlkdtmeveeflkeaavmkeikhpnlvql
lgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameylekknfih
rdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfsiksd
vwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnps
drpsfaeihqafetmfqes

SCOPe Domain Coordinates for d2hz4c_:

Click to download the PDB-style file with coordinates for d2hz4c_.
(The format of our PDB-style files is described here.)

Timeline for d2hz4c_: