SCOPe 2.05: Domain d2fn7a2: 2fn7 A:165-333

Lineage for d2fn7a2 (2fn7 A:165-333)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (18 species)

7. Species Cryptosporidium parvum [TaxId:5807] [225186] (6 PDB entries)

8. Domain d2fn7a2: 2fn7 A:165-333 [204244]
   Other proteins in same PDB: d2fn7a1, d2fn7b1
   automated match to d1ez4a2
   complexed with gol, lac, nad

Details for d2fn7a2

PDB Entry: 2fn7, 2.3 Å

PDB Description: crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (lactic acid) and cofactor (b- nicotinamide adenine dinucleotide)

PDB Compounds: (A:) lactate dehydrogenase

SCOPe Domain Sequences for d2fn7a2:

Sequence; same for both SEQRES and ATOM records:

>d2fn7a2 d.162.1.1 (A:165-333) Lactate dehydrogenase {Cryptosporidium parvum [TaxId: 5807]}
gvldssrfrtfiaqhfgvnasdvsanvigghgdgmvpatssvsvggvplssfikqglitq
eqideivchtriawkevadnlktgtayfapaaaavkmaeaylkdkkavvpcsafcsnhyg
vkgiymgvptiigkngvedileldltpleqkllgesinevntiskvldnap

Timeline for d2fn7a2:

• d2fn7a2 first appeared in SCOPe 2.03
  
• d2fn7a2 appears in SCOPe 2.04
  
• d2fn7a2 appears in SCOPe 2.06
  
• d2fn7a2 appears in the current release, SCOPe 2.08