SCOPe 2.08: Domain d1c5dh1: 1c5d H:1-117

Lineage for d1c5dh1 (1c5d H:1-117)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [88560] (16 PDB entries)

8. Domain d1c5dh1: 1c5d H:1-117 [20413]
   Other proteins in same PDB: d1c5da1, d1c5da2, d1c5db2, d1c5dh2, d1c5dl1, d1c5dl2
   part of antibody against the main immunogenic region of the human muscle acetylcholine receptor

Details for d1c5dh1

PDB Entry: 1c5d, 2.4 Å

PDB Description: the crystal structure of the fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor

PDB Compounds: (H:) monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor

SCOPe Domain Sequences for d1c5dh1:

Sequence; same for both SEQRES and ATOM records:

>d1c5dh1 b.1.1.1 (H:1-117) Immunoglobulin heavy chain variable domain, VH {Norway rat (Rattus norvegicus) [TaxId: 10116]}
evkllesgpglvqpsqtlsltctvsgfplttngvswvrqppgkglewiaaissggspyyn
salksrlsinrdtsksqvflkmnslqtedtaiyfctredgwnyfdywgpgtmvtvss

Timeline for d1c5dh1:

• d1c5dh1 first appeared (with stable ids) in SCOP 1.55
  
• d1c5dh1 appears in SCOPe 2.07