SCOPe 2.08: Domain d2c2xb2: 2c2x B:122-281

Lineage for d2c2xb2 (2c2x B:122-281)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [186789] (19 PDB entries)

8. Domain d2c2xb2: 2c2x B:122-281 [203712]
   Other proteins in same PDB: d2c2xa1, d2c2xb1
   automated match to d1a4ia1

Details for d2c2xb2

PDB Entry: 2c2x, 2 Å

PDB Description: three dimensional structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from mycobacterium tuberculosis

PDB Compounds: (B:) methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase

SCOPe Domain Sequences for d2c2xb2:

Sequence; same for both SEQRES and ATOM records:

>d2c2xb2 c.2.1.0 (B:122-281) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
lhptnlgrlvlgtpaplpctprgivhllrrydisiagahvvvigrgvtvgrplgllltrr
senatvtlchtgtrdlpaltrqadivvaavgvahlltadmvrpgaavidvgvsrtddglv
gdvhpdvwelaghvspnpggvgpltraflltnvvelaerr

Timeline for d2c2xb2:

• d2c2xb2 first appeared in SCOPe 2.03
  
• d2c2xb2 appears in SCOPe 2.07