SCOPe 2.03: Domain d2c0ia2: 2c0i A:121-223

Lineage for d2c0ia2 (2c0i A:121-223)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.93: SH2-like [55549] (1 superfamily)
   3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices

4. Superfamily d.93.1: SH2 domain [55550] (2 families)

5. Family d.93.1.1: SH2 domain [55551] (35 proteins)
   Pfam PF00017

6. Protein Hemopoetic cell kinase Hck [55565] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55566] (17 PDB entries)

8. Domain d2c0ia2: 2c0i A:121-223 [203665]
   Other proteins in same PDB: d2c0ia1, d2c0ia3, d2c0ib1, d2c0ib3
   automated match to d1qcfa2
   complexed with ca, l1g

Details for d2c0ia2

PDB Entry: 2c0i, 2.3 Å

PDB Description: src family kinase hck with bound inhibitor a-420983

PDB Compounds: (A:) Tyrosine-protein kinase HCK

SCOPe Domain Sequences for d2c0ia2:

Sequence; same for both SEQRES and ATOM records:

>d2c0ia2 d.93.1.1 (A:121-223) Hemopoetic cell kinase Hck {Human (Homo sapiens) [TaxId: 9606]}
eewffkgisrkdaerqllapgnmlgsfmirdsettkgsyslsvrdydprqgdtvkhykir
tldnggfyisprstfstlqelvdhykkgndglcqklsvpcmss

Timeline for d2c0ia2:

• d2c0ia2 is new in SCOPe 2.03-stable
  
• d2c0ia2 appears in SCOPe 2.04
  
• d2c0ia2 appears in the current release, SCOPe 2.08