SCOPe 2.02: Domain d1qful1: 1qfu L:1-106B

Lineage for d1qful1 (1qfu L:1-106B)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (15 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)
   Uniprot P01631 #KV2G_MOUSE Ig kappa chain V-II region 26-10; 79% sequence identity ! Uniprot P06310 # KV2F_HUMAN IG KAPPA CHAIN V-II REGION RPMI 6410 PRECURSOR ! Uniprot P03976 # KV2E_MOUSE (P03976) Ig kappa chain V-II region 17S29.1 ! Uniprot P01642 21-115 # ! KV2G_MOUSE IG KAPPA CHAIN V-II REGION 26-10

8. Domain d1qful1: 1qfu L:1-106B [20292]
   Other proteins in same PDB: d1qfua_, d1qfub_, d1qfuh1, d1qfuh2, d1qful2
   part of Influenza virus hemagglutinin-neutralizing Fab
   complexed with nag

Details for d1qful1

PDB Entry: 1qfu, 2.8 Å

PDB Description: influenza virus hemagglutinin complexed with a neutralizing antibody

PDB Compounds: (L:) protein (immunoglobulin igg1-kappa antibody (light chain))

SCOPe Domain Sequences for d1qful1:

Sequence; same for both SEQRES and ATOM records:

>d1qful1 b.1.1.1 (L:1-106B) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
dvvmtqtplslpvslgdqasiscrssqtlvhsngntylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqnthvpytfgggtkleik

Timeline for d1qful1:

• d1qful1 first appeared (with stable ids) in SCOP 1.55
  
• d1qful1 appears in SCOPe 2.01
  
• d1qful1 appears in SCOPe 2.03
  
• d1qful1 appears in the current release, SCOPe 2.08