Lineage for d4kind_ (4kin D:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1930891Protein MAP kinase p38 [56129] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 1930892Species Human (Homo sapiens) [TaxId:9606] [56130] (162 PDB entries)
  8. 1930913Domain d4kind_: 4kin D: [202863]
    automated match to d2rg6a_
    complexed with 1m8

Details for d4kind_

PDB Entry: 4kin (more details), 1.97 Å

PDB Description: crystal structure of mitogen-activated protein kinase 14 (p38-h5) complex with 5-(2-chlorophenyl)-n-(5-(cyclopropylcarbamoyl)-2-methylphenyl)-2-thiophenecarboxamide
PDB Compounds: (D:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d4kind_:

Sequence, based on SEQRES records: (download)

>d4kind_ d.144.1.7 (D:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsii
hakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqklt
ddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyv
atrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpg
aellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqal
ahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records): (download)

>d4kind_ d.144.1.7 (D:) MAP kinase p38 {Human (Homo sapiens) [TaxId: 9606]}
erptfyrqelnktiwevperyqnlspvaygsvcaafdtktglrvavkklsrpfqsiihak
rtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddh
vqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhatrwyrapeiml
nwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesa
rnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpd
depvadpydqsfesrdllidewksltydevisfvpppld

SCOPe Domain Coordinates for d4kind_:

Click to download the PDB-style file with coordinates for d4kind_.
(The format of our PDB-style files is described here.)

Timeline for d4kind_: