SCOPe 2.01: Domain d1a6wl_: 1a6w L:

Lineage for d1a6wl_ (1a6w L:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
   VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family

7. Species Mouse (Mus musculus) [TaxId:10090] [88541] (34 PDB entries)

8. Domain d1a6wl_: 1a6w L: [20252]
   Other proteins in same PDB: d1a6wh_
   part of Fv B1-8
   complexed with nip

Details for d1a6wl_

PDB Entry: 1a6w, 2 Å

PDB Description: b1-8 fv fragment complexed with a (4-hydroxy-5-iodo-3-nitrophenyl) acetate compound

PDB Compounds: (L:) b1-8 fv (light chain)

SCOPe Domain Sequences for d1a6wl_:

Sequence; same for both SEQRES and ATOM records:

>d1a6wl_ b.1.1.1 (L:) Immunoglobulin light chain lambda variable domain, VL-lambda {Mouse (Mus musculus) [TaxId: 10090]}
avvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggtnnrapgvp
arfsgslignkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvle

Timeline for d1a6wl_:

• d1a6wl_ first appeared (with stable ids) in SCOP 1.55
  
• d1a6wl_ appears in SCOP 1.75
  
• d1a6wl_ appears in SCOPe 2.02
  
• d1a6wl_ appears in the current release, SCOPe 2.08