SCOPe 2.04: Domain d4glwa_: 4glw A:

Lineage for d4glwa_ (4glw A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.2: DNA ligase/mRNA capping enzyme, catalytic domain [56091] (6 families)
   has a circularly permuted topology

5. Family d.142.2.2: Adenylation domain of NAD+-dependent DNA ligase [56096] (2 proteins)
   automatically mapped to Pfam PF01653

6. Protein automated matches [194553] (2 species)
   not a true protein

7. Species Streptococcus pneumoniae [TaxId:488223] [194554] (1 PDB entry)

8. Domain d4glwa_: 4glw A: [202278]
   automated match to d4glwb_
   protein/DNA complex; complexed with 0xt, nmn, so4

Details for d4glwa_

PDB Entry: 4glw, 2 Å

PDB Description: dna ligase a in complex with inhibitor

PDB Compounds: (A:) DNA ligase

SCOPe Domain Sequences for d4glwa_:

Sequence, based on SEQRES records:

>d4glwa_ d.142.2.2 (A:) automated matches {Streptococcus pneumoniae [TaxId: 488223]}
nkrmnelvallnryateyytsdnpsvsdseydrlyrelveletaypeqvladspthrvgg
kvldgfekyshqyplyslqdafsreeldafdarvrkevahptyicelkidglsisltyek
gilvagvtrgdgsigenitenlkrvkdipltlpeelditvrgecymprasfdqvnqarqe
ngepefanprnaaagtlrqldtavvakrnlatflyqeaspstrdsqekglkyleqlgfvv
npkrilaenideiwnfiqevgqerenlpydidgvvikvndlasqeelgftvkapkwavay
kfpa

Sequence, based on observed residues (ATOM records):

>d4glwa_ d.142.2.2 (A:) automated matches {Streptococcus pneumoniae [TaxId: 488223]}
nkrmnerelveletaypeqvladspthrvggkvldgfekyshqyplyslqdafsreelda
fdarvrkevahptyicelkidglsisltyekgilvagvtrgdgsigenitenlkrvkdip
ltlpeelditvrgecymprasfdqvnqarqengepefanprnaaagtlrqldtavvakrn
latflyqeaspstrdsqekglkyleqlgfvvnpkrilaenideiwnfiqevgqerenlpy
didgvvikvndlasqeelgftvkapkwavaykfpa

Timeline for d4glwa_:

• d4glwa_ first appeared in SCOPe 2.03
  
• d4glwa_ appears in SCOPe 2.05
  
• d4glwa_ appears in the current release, SCOPe 2.08