SCOPe 2.04: Domain d4bcmd2: 4bcm D:309-428

Lineage for d4bcmd2 (4bcm D:309-428)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (9 proteins)

6. Protein automated matches [227027] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225840] (6 PDB entries)

8. Domain d4bcmd2: 4bcm D:309-428 [201608]
   Other proteins in same PDB: d4bcma_, d4bcmc_
   automated match to d2cchb2
   complexed with sgm, t7z

Details for d4bcmd2

PDB Entry: 4bcm, 2.45 Å

PDB Description: Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor

PDB Compounds: (D:) Cyclin-A2

SCOPe Domain Sequences for d4bcmd2:

Sequence, based on SEQRES records:

>d4bcmd2 a.74.1.1 (D:309-428) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptvnqfltqyflhqqpanckvellamflgelslidadpylkylpsviagaafhlalytvt
gqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyknskyhgvsllnppe

Sequence, based on observed residues (ATOM records):

>d4bcmd2 a.74.1.1 (D:309-428) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptvnqfltqyflhllamflgelslidadpylkylpsviagaafhlawpeslirktgytle
slkpclmdlhqtylkapqhaqqsirekyknskyhgvsllnppe

Timeline for d4bcmd2:

• d4bcmd2 first appeared in SCOPe 2.03
  
• d4bcmd2 appears in SCOPe 2.05
  
• d4bcmd2 appears in the current release, SCOPe 2.08