SCOPe 2.03: Domain d4b8wb_: 4b8w B:

Lineage for d4b8wb_ (4b8w B:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (159 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186944] (28 PDB entries)

8. Domain d4b8wb_: 4b8w B: [201581]
   automated match to d4b8wa_
   complexed with gdp, nap

Details for d4b8wb_

PDB Entry: 4b8w, 2.75 Å

PDB Description: crystal structure of human gdp-l-fucose synthase with bound nadp and gdp, tetragonal crystal form

PDB Compounds: (B:) GDP-l-fucose synthase

SCOPe Domain Sequences for d4b8wb_:

Sequence, based on SEQRES records:

>d4b8wb_ c.2.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfqsmrilvtggsglvgkaiqkvvadgaglpgedwvfvsskdadltdtaqtralfekvqp
thvihlaamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdktt
ypidetmihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfnie
dghvlpglihkvhlakssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiils
vgeedevsikeaaeavveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkq
avketcawftdnye

Sequence, based on observed residues (ATOM records):

>d4b8wb_ c.2.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfqsmrilvtggsglvgkaiqkvvapgedwvfvsskdadltdtaqtralfekvqpthvih
laamvnldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypidetmihngpph
nsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedghvlpglihkvhl
akssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvgeedevsikeaae
avveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkqavketcawftdnye

Timeline for d4b8wb_:

• d4b8wb_ is new in SCOPe 2.03-stable
  
• d4b8wb_ appears in SCOPe 2.04
  
• d4b8wb_ appears in the current release, SCOPe 2.08, called d4b8wb1