SCOP 1.65: Domain d1keml1: 1kem L:1-112

Lineage for d1keml1 (1kem L:1-112)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogeneous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (98 PDB entries)

8. Domain d1keml1: 1kem L:1-112 [20114]
   Other proteins in same PDB: d1kemh1, d1kemh2, d1keml2
   part of Fab 28B4

Details for d1keml1

PDB Entry: 1kem, 2.2 Å

PDB Description: catalytic antibody 28b4 fab fragment

SCOP Domain Sequences for d1keml1:

Sequence; same for both SEQRES and ATOM records:

>d1keml1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
dvlmtqtplslpvslgdqasiscrfsqsivhsngntylewylqksgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyycfqgshvprtfgggtkleik

Timeline for d1keml1:

• d1keml1 first appeared (with stable ids) in SCOP 1.55
  
• d1keml1 appears in SCOP 1.63
  
• d1keml1 appears in SCOP 1.67
  
• d1keml1 appears in the current release, SCOPe 2.08