SCOP 1.73: Domain d1nmah_: 1nma H:

Lineage for d1nmah_ (1nma H:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (148 PDB entries)

8. Domain d1nmah_: 1nma H: [20065]
   Other proteins in same PDB: d1nmal_, d1nman_
   part of Fab NC10; only Fv coordinates are included
   complexed with man, nag; mutant

Details for d1nmah_

PDB Entry: 1nma, 3 Å

PDB Description: n9 neuraminidase complexes with antibodies nc41 and nc10: empirical free-energy calculations capture specificity trends observed with mutant binding data

PDB Compounds: (H:) fab nc10

SCOP Domain Sequences for d1nmah_:

Sequence; same for both SEQRES and ATOM records:

>d1nmah_ b.1.1.1 (H:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
evqlqqpgaelvkpgasvrmsckasgytftnynmywvkqspgqglewigifypgngdtsy
nqkfkdkatltadkssntaymqlssltsedsavyycarsggsyrydggfdywgqgttltv
ss

Timeline for d1nmah_:

• d1nmah_ first appeared (with stable ids) in SCOP 1.55
  
• d1nmah_ appears in SCOP 1.71
  
• d1nmah_ appears in SCOP 1.75
  
• d1nmah_ appears in the current release, SCOPe 2.08