SCOP 1.69: Domain d1mlba1: 1mlb A:1-108

Lineage for d1mlba1 (1mlb A:1-108)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (162 PDB entries)

8. Domain d1mlba1: 1mlb A:1-108 [20050]
   Other proteins in same PDB: d1mlba2, d1mlbb1, d1mlbb2
   part of Fab D44.1

Details for d1mlba1

PDB Entry: 1mlb, 2.1 Å

PDB Description: monoclonal antibody fab d44.1 raised against chicken egg-white lysozyme

SCOP Domain Sequences for d1mlba1:

Sequence; same for both SEQRES and ATOM records:

>d1mlba1 b.1.1.1 (A:1-108) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
dieltqspatlsvtpgdsvslscrasqsisnnlhwyqqkshesprllikyvsqsssgips
rfsgsgsgtdftlsinsvetedfgmyfcqqsnswprtfgggtkleikr

Timeline for d1mlba1:

• d1mlba1 first appeared (with stable ids) in SCOP 1.55
  
• d1mlba1 appears in SCOP 1.67
  
• d1mlba1 appears in SCOP 1.71
  
• d1mlba1 appears in the current release, SCOPe 2.08