SCOPe 2.08: Domain d3r1gl2: 3r1g L:108-214

Lineage for d3r1gl2 (3r1g L:108-214)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein automated matches [190374] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187221] (1251 PDB entries)

8. Domain d3r1gl2: 3r1g L:108-214 [200429]
   Other proteins in same PDB: d3r1gb1, d3r1gb2, d3r1gl1
   automated match to d1rhha2

Details for d3r1gl2

PDB Entry: 3r1g, 2.8 Å

PDB Description: Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody

PDB Compounds: (L:) FAB of YW412.8.31 antibody light chain

SCOPe Domain Sequences for d3r1gl2:

Sequence; same for both SEQRES and ATOM records:

>d3r1gl2 b.1.1.2 (L:108-214) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d3r1gl2:

• d3r1gl2 first appeared in SCOPe 2.03
  
• d3r1gl2 appears in SCOPe 2.07