Lineage for d1rmfh1 (1rmf H:1-119)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1510240Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1510241Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1510242Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1510447Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1510931Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (178 PDB entries)
    Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor
  8. 1511074Domain d1rmfh1: 1rmf H:1-119 [20029]
    Other proteins in same PDB: d1rmfh2, d1rmfl1, d1rmfl2
    part of Fab R6.5

Details for d1rmfh1

PDB Entry: 1rmf (more details), 2.8 Å

PDB Description: structures of a monoclonal anti-icam-1 antibody r6.5 fragment at 2.8 angstroms resolution
PDB Compounds: (H:) igg2a-kappa r6.5 fab (heavy chain)

SCOPe Domain Sequences for d1rmfh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1rmfh1 b.1.1.1 (H:1-119) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]}
qvqlqqsgpelvrpgvsvkisckgsgytfidyaihwvkeshakslewigvisaysgdtny
nqkfkgkatmtvdkssntaylelarltsedsaiyycarggwlllsfdywgqgttltvss

SCOPe Domain Coordinates for d1rmfh1:

Click to download the PDB-style file with coordinates for d1rmfh1.
(The format of our PDB-style files is described here.)

Timeline for d1rmfh1:

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Domains from same chain:
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d1rmfh2